Modern Medicine on Polygonatum

The 2015 edition of the Pharmacopoeia of the People’s Republic of China states that Polygonatum sibiricum is sweet and neutral; it enters the spleen, lung, and kidney meridians. Functions: replenishing qi and nourishing yin, strengthening the spleen, moistening the lungs, and benefiting the kidneys. Indications: spleen and stomach weakness, fatigue, dry mouth and poor appetite, lung deficiency and dry cough, insufficient essence and blood, soreness of waist and knees, premature graying of hair, internal heat and thirst. Modern pharmacological experiments show that the main components of Polygonatum sibiricum are Polygonatum sibiricum polysaccharides, Polygonatum sibiricum oligosaccharides, steroidal saponins, Kun, mucus, amino acids and trace elements such as calcium, magnesium, zinc, iron, and selenium, and the content is extremely rich. Based on modern scientific research, the specific effects of Polygonatum sibiricum are as follows: Three-lowering, lowering blood sugar. Polygonatum sibiricum can increase the insulin content in human serum, and thus has a significant blood sugar-lowering effect, especially for hyperglycemia caused by adrenal hormone imbalance. Lowering blood lipids
Polygonatum odoratum decoction can significantly reduce the total triglyceride and total cholesterol content in human blood to prevent and treat arteriosclerosis and fatty liver infiltration, so it has the function of assisting in lowering blood lipids.
Lowering blood pressure
Polygonatum odoratum polysaccharide can enhance cardiac contractility, increase coronary artery flow, improve blood rheology parameters and atherosclerotic lesions, and also has the effect of assisting in lowering blood pressure
Six anti-tumor
Polygonatum odoratum polysaccharide can induce programmed cell death of cancer cells and induce autophagy of cancer cells by mitochondrial membrane, so it has anti-tumor effect.
Anti-aging
Polygonatum odoratum can harmonize the five internal organs, improve physical fitness, regulate body functions, balance the internal environment of the body, thereby delaying the aging process, so it has anti-aging effect.
Anti-radiation
Polygonatum odoratum has the effect of treating electromagnetic radiation-induced male infertility due to kidney essence deficiency, and can restore the damaged male reproductive function, so it has anti-radiation effect.
Anti-disease
The active ingredients in Polygonatum sibiricum can effectively resist herpes simplex virus, and also have a strong inhibitory effect on most bacteria, actinomycetes, and unicellular fungi, so it has anti-viral and anti-bacterial effects.
Anti-oxidation
Polygonatum sibiricum can inhibit the production of spontaneous and induced lipid peroxides, and can directly scavenge active oxygen free radicals, so it has an antioxidant effect.
Anti-dementia
Dementia is also known as “Alzheimer’s disease”. Polygonatum sibiricum decoction can significantly shorten the escape latency of rats with AD model induced by B amyloid protein, and improve hippocampal pathological damage by reducing the phosphorylation of u protein at Thr231 in the CA1 region, enhancing the learning and memory ability of rats, and ultimately preventing Alzheimer’s disease.
Two improvements
Improve immunity
Polygonatum sibiricum can promote the formation of immunoglobulins, improve the body’s disease resistance, and increase the activity of superoxide dismutase in the body, so it has the effect of improving immunity.
Improve memory
Polygonatum is sweet and mild in nature, and is a mild tonic. Long-term use can promote the recovery of brain function, thus
improving memory.